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Health, Wellness, Sex and Body Discuss New aggressive strain of HIV can progress to AIDS in just three years, scientists war at the General Discussion; New aggressive strain of HIV can progress to AIDS in just three years, scientists warn | Daily Mail Online Feb ...

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Old 02-16-2015, 01:12 PM
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Default New aggressive strain of HIV can progress to AIDS in just three years, scientists war

New aggressive strain of HIV can progress to AIDS in just three years, scientists warn | Daily Mail Online

Feb 16 2015

Quote:
An aggressive new strain of HIV has been identified, scientists have warned.
A new study found the strain, called CRF19, is capable of transforming from an infection to full-blown aids within just three years.
That is considerably faster than the average conversion time of around 10 years - and can be so quick that a person may not even realise they are infected.
Scientists were prompted to investigate after noting a growing number of reports of people in Cuba suffering a rapid progression to AIDS, within three years of infection.
Just in time for relaxed travel restrictions to Cuba! You know, in case opening the southern border to a resurgence of previously vanquished diseases wasn't enough.
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Old 03-19-2017, 12:46 AM
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Lightbulb Re: New aggressive strain of HIV can progress to AIDS in just three years, scientists

A bid to avert new infections...

Kenya to Roll Out Drug to Curb HIV Infection
March 17, 2017 — Thousands of HIV-negative Kenyans will for the first time be placed on daily antiretroviral medication, or ARVs, in a bid to avert new infections. The new program seeks to lower the country's HIV transmission rate to individuals who face a substantial risk of contracting HIV, such as rape victims and HIV-negative drug users.
Quote:
The head of the National AIDS and STI Control Program (NASCOP), Martin Sirengo, said the measure will be rolled out in April and will involve the use of Pre-exposure Prophylaxis, or PrEP. “We are introducing PrEP to a selected population, not to everyone, and this selected population includes, for instance, HIV-negative partners in a discordant relationship, where the other partner is positive,” Sirengo said. “Anyone who comes and gives a history of repeated sexually transmitted infections, anyone who comes for repeated PrEP medication, that tells us they are at risk of getting HIV," will be eligible, he said. "We are also recommending PrEP to anyone who has multiple sexual partners.”

Drugs are very effective

If taken daily, the drugs have a success rate of preventing HIV infection of more than 96 percent, according to pilot studies conducted in Kenya by NASCOP and the Partners Prevention Program between 2013 and 2016. “Only four out of the over 1,500 [tested] got infected [with] HIV, which means prep is highly effective to the tune of over 96 percent or more,” Sirengo said. “And, when we look at the four that got positive, we actually realized they were not adhering to the treatment.” Kenya becomes the second country in Africa, after South Africa, to roll out PrEP. However, it is widely used in developed countries.

Some aren't so sure

Some are still skeptical about the drug. Esther Atieno is a commercial sex worker. She says she prefers to use alternative methods. “I don't think many people will use it,” Atieno said. “There is no one who likes to take medication every day. The condom is the best protective method because it is not something you use every day like the daily pill.”

Drugs free in public facilities

Sirengo agrees that users should combine PrEP with other preventive interventions, like use of condoms and male circumcision to further reduce the risk of acquiring HIV. The cost of the treatment is between $500 to $800 a person per year, but it is expected NGOs and other partners will subsidize the treatment.


Post-exposure prophylaxis requires taking antiretroviral medicines after being potentially exposed to HIV to prevent becoming infected. The drugs can prevent HIV infection by more than 96 percent

The drugs will be free in all public facilities, but those who seek treatment in private health facilities will have to purchase the drugs for $60-$100 per annual treatment. Sirengo says trained health workers will assess who qualifies for this treatment. It is anticipated that the drug will avert many new infections in Kenya, reported to have the fourth-highest HIV infection in the world. An estimated 1.5 million Kenyans are said to be living with the virus.

Kenya to Roll Out Drug to Curb HIV Infection
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Old 09-22-2017, 07:51 AM
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Lightbulb Re: New aggressive strain of HIV can progress to AIDS in just three years, scientists

A cure for AIDS on the horizon?...

New antibody attacks 99% of HIV strains
22 September 2017 - Scientists have engineered an antibody that attacks 99% of HIV strains and can prevent infection in primates.
Quote:
It is built to attack three critical parts of the virus - making it harder for HIV to resist its effects. The work is a collaboration between the US National Institutes of Health and the pharmaceutical company Sanofi. The International Aids Society said it was an "exciting breakthrough". Human trials will start in 2018 to see if it can prevent or treat infection. Our bodies struggle to fight HIV because of the virus' incredible ability to mutate and change its appearance. These varieties of HIV - or strains - in a single patient are comparable to those of influenza during a worldwide flu season. So the immune system finds itself in a fight against an insurmountable number of strains of HIV.

Super-antibodies

But after years of infection, a small number of patients develop powerful weapons called "broadly neutralising antibodies" that attack something fundamental to HIV and can kill large swathes of HIV strains. Researchers have been trying to use broadly neutralising antibodies as a way to treat HIV, or prevent infection in the first place. The study, published in the journal Science, combines three such antibodies into an even more powerful "tri-specific antibody".


Dr Gary Nabel, the chief scientific officer at Sanofi and one of the report authors, told the BBC News website: "They are more potent and have greater breadth than any single naturally occurring antibody that's been discovered." The best naturally occurring antibodies will target 90% of HIV strains. "We're getting 99% coverage, and getting coverage at very low concentrations of the antibody," said Dr Nabel. Experiments on 24 monkeys showed none of those given the tri-specific antibody developed an infection when they were later injected with the virus. Dr Nabel said: "It was quite an impressive degree of protection." The work included scientists at Harvard Medical School, The Scripps Research Institute, and the Massachusetts Institute of Technology.

'Exciting'
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