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Health, Wellness, Sex and Body Discuss Discovered: The 'insomnia' gene that means you sleep two-thirds less than normal at the General Discussion; Discovered: The 'insomnia' gene that means you sleep two-thirds less than normal (... and don't live as long) Last updated ...

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Old 02-27-2012, 07:10 PM
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Exclamation Discovered: The 'insomnia' gene that means you sleep two-thirds less than normal

Discovered: The 'insomnia' gene that means you sleep two-thirds less than normal (... and don't live as long)

Last updated at 8:31 AM on 22nd February 2012

An 'insomnia gene' has been discovered by scientists.


Experiments on fruit flies found those carrying a mutation in the protein slept two thirds less than normal - and also had much shorter lifespans.

Previous studies have found men, in particular, are significantly more likely to die early if they suffer from chronic shortage of sleep with the problem linked to conditions such as high blood pressure and diabetes.

The latest research says although flies and humans have little in common when it comes to lifestyle, the mechanisms of sleep and wakefulness are likely to be quite similar.

Dr Nicholas Stavropoulos, of Rockefeller University in New York, said: "Sleep is a fundamental behaviour in all animals, and it is poorly understood from a scientific standpoint.

"This work gives us several new clues about how sleep is controlled at the molecular level, and could prove useful in understanding and treating sleep disorders."

By cloning and testing the gene, known as insomniac, in more than 20,000 fruit flies his team say they have discovered an entirely new mechanism by which sleep is regulated.

Using an infrared beam to detect when the flies nodded off, they discovered those with the variant slept for an average of just 317 minutes a day instead of the typical amount of 927 minutes. The mutant flies also snoozed for shorter periods, and slept and woke more frequently.

Dr Stavropoulos said: "The results showed a dramatic loss of both the duration of the flies' sleep and their ability to remain asleep after they dozed off.
"But what's especially interesting is the insomniac gene may function through homeostatic mechanisms.

"These are distinct from the well-studied circadian clock pathways linked to sleep, and have an effect on the body regardless of the time of day."

The scientists believe the gene works by eliminating specific proteins within brain cells that help in the onset of sleep.

The researchers also found flies with mutations lived only about two thirds as long as others.

But when the scientists eliminated the gene from neurons - allowing it to remain in the rest of the flies' bodies - this disparity was eliminated. The resulting animals slept poorly but lived just as long.

Dr Stavropoulos said: "This suggests reduced sleep can be 'uncoupled' from reduced lifespan, supporting the idea some disruptions of sleep do not effect overall health, at least as far as lifespan is concerned."

'Insomnia' gene means you sleep two-thirds less than normal and don't live as long | Mail Online
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Old 02-27-2012, 07:31 PM
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Default Re: Discovered: The 'insomnia' gene that means you sleep two-thirds less than normal

well thanks, scientists. some **** you might wanna just keep to yourself.
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Old 02-28-2012, 12:32 AM
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Default Re: Discovered: The 'insomnia' gene that means you sleep two-thirds less than normal

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Originally Posted by saltwn View Post
well thanks, scientists. some **** you might wanna just keep to yourself.
Don't worry too much. It is the last sentence which counters what we have thought in the past; that reduced sleep shortens a person's lifespan.
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Old 09-10-2017, 03:32 PM
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Red face Re: Discovered: The 'insomnia' gene that means you sleep two-thirds less than normal

Uncle Ferd gets depressed when his g/f don't give him some nookie...

Study: Treating Insomnia Eases Anxiety, Depression
September 06, 2017 — Treating young people who suffer from insomnia by using online cognitive behavioral therapy (CBT) could reduce debilitating mental health problems such as anxiety and depression, scientists said Wednesday.
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In a large trial published in The Lancet Psychiatry journal, researchers at Oxford University’s Sleep and Circadian Neuroscience Institute also found that successfully treating sleep disruption eased psychotic symptoms such as hallucinations and paranoia. “Sleep problems are very common in people with mental health disorders, but for too long insomnia has been trivialized as merely a symptom, rather than a cause, of psychological difficulties,” said Daniel Freeman, a professor of clinical psychology who led the work. “This study turns that old idea on its head, showing that insomnia may actually be a contributory cause of mental health problems.”]



A study published Wednesday found that treating insomnia in young people could ease mental health problems such as anxiety and depression.

The research involved 3,755 university students from across Britain who were randomized into two groups. One group had six sessions of online CBT, each lasting about 20 minutes, and delivered via a digital program called Sleepio. The others had access to standard treatments but no CBT. Free man’s team monitored participants’ mental health with a series of online questionnaires at zero, three, 10 and 22 weeks from the start of treatment. The researchers found that those who had the CBT sleep treatment reduced their insomnia significantly as well as showing small but sustained reductions in paranoia and hallucinatory experiences.

The CBT also led to improvements in depression, anxiety, nightmares, psychological well-being, and daytime work and home functioning. Andrew Welchman, head of neuroscience and mental health at the Wellcome Trust health charity, which helped fund the research, said the results suggested improving sleep may provide a promising route into early treatment to improve mental health. Freeman added: “A good night’s sleep really can make a difference to people’s psychological health. Helping people get better sleep could be an important first step in tackling many psychological and emotional problems.”

https://www.voanews.com/a/study-trea...n/4018574.html
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